Symantec Email Proxy Error 1003,10 and 1003,8

We have two clients working on an application used internally. There is a webconfig which calls the SMTP service on Port 25 to recieve emails each time a workflow is excuted.

Here on the localhost the workflow is executed successfully but only the notifcation is blocked by symantec as shown attached.

SEP client was recently updated SEP 12.1.6860.6400.

Pls tell me how can I resolve this error