Enable secure communications between the management server and clients

Hi All,

I saw similar discussion on the forum but didn't see the answer of this question. Attached is a screenshot.

I need to know if there is relation between the option "Enable secure communications between the management server and clients by using digital cetrtificates for authentication" which is under Client group -> Policies -> General Settings -> Secure settings and the option in Management Server List for HTTPS communication.

Note that we are using HTTP communication on port 8014 and the option for secure communication in General settings is checked. However on few groups somebody un-checked it. If we check it, will this cause any communication issues between the machines from this group and the SEPM?

Thanks in advance